Which alternative prescription medications are effective in treating hot flash symptoms of menopause?
A few prescription medications, in addition to estrogen, can provide relief for hot flashes. While none of these drugs is as effective as estrogen, studies show that non-estrogen drugs may have up to 70% of the effectiveness of estrogen therapy when treating hot flashes. • Selective serotonin reuptake inhibitors (SSRI’s): This class of medication is used to treat depression and anxiety. In clinical studies, however, low doses of SSRI’s have been shown to be effective in decreasing menopausal hot flashes. The SSRI that has been tested most extensively is venlafaxine (Effexor), although there is also evidence showing that paroxetine (Paxil, Paxil CR) and fluoxetine (Prozac) can be effective in controlling hot flashes. • Clonidine: Clonidine (Catapres) acts in the brain to decrease blood pressure. It has a long history of being used for blood pressure control, but it has potentially annoying side effects, such as dry mouth, constipation, drowsiness, or difficulty sleeping. Clonidine effec