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Where does Synvisc fit into the sequence of treatments for osteoarthritis of the knee?

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Where does Synvisc fit into the sequence of treatments for osteoarthritis of the knee?

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Synvisc is indicated for the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics, e.g. acetaminophen, which occurs before NSAID therapy. Synvisc has been shown to be effective in all stages of OA, although it is most effective in the early stages of this disease.

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