Where does ACC typically show up the first time?
ACC primary tumors occur in 38 different organs of the body, with approximately 58% occurring in the head and neck region. Overall, salivary gland cancers account for about 3% of all malignant head and neck cancers in North America, and out of that 3%, about 25% to 40% are ACC. Of all salivary gland tumors only about 10% to 15% are of minor salivary gland origin. ACC has a higher tendency to occur in hundreds of minor salivary glands than in the major salivary glands, which are the two large parotid glands in the cheek areas and the submandibular and sublingual glands towards the bottom of the mouth. There have been documented cases of other primary sites besides head and neck and these include breast, bone, lung, liver and other organs, but these sites are more commonly the result of metastic disease from tumors with the primary site being in the head and neck. ACC has a very low rate of infiltrating the lymph system, though it can occur.
Related Questions
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