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DESCRIPTION This drug inhibits serotonin reuptake by neurons, promoting increases in levels of serotonin, an important neurotransmitter in mood disorders. ORIGINAL USES (ON-LABEL) Depression, generalized anxiety disorder. NEWLY DISCOVERED USES (OFF-LABEL) Premenstrual dysphoric disorder (PMDD). POTENTIAL SIDE EFFECTS Somnolence, insomnia, nausea, dry mouth, sweating, anxiety, anorexia, agitation, yawning, rash, itching, sexual dysfunction, diarrhea, stomach upset, vomiting, abdominal pain, tremor, weight gain, joint aches, muscle aches, cough, rhinitis, sinusitis, low sodium levels. CAUTIONS • Do not use concurrently with MAO inhibitors or within two weeks of discontinuing MAO-I. • Inform your doctor if you have a history of mania or seizures, or if you have kidney dysfunction. • Use caution if you are a high-risk suicide attempt patient during initiation of therapy. • Has potential to impair cognitive/motor performance; you should use caution operating hazardous machinery. • Elderly p
