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DESCRIPTION This drug inhibits the activity of a certain enzyme in the central nervous system, which slows abnormal and excessive discharge from central nervous system neurons. This action also results in a decreased pressure. ORIGINAL USES (ON-LABEL) Glaucoma (chronic simple open-angle, secondary glaucoma, preoperatively in acute angle-closure), drug-induced edema (swelling related to fluid retention) or edema due to congestive heart failure, some types of seizures (immediate release dosage form), prevention or amelioration of symptoms associated with acute mountain sickness. NEWLY DISCOVERED USES (OFF-LABEL) Meniere’s Disease POTENTIAL SIDE EFFECTS Flushing, incoordination of muscles, confusion, depression, allergic skin reaction, photosensitivity (skin reaction related to sun exposure), electrolyte imbalance, increased blood or urine glucose, appetite decreased, diarrhea, nausea, frequent urination, blood disorders, liver disorders, numbness, hearing disturbance, ringing in the ears
