When was propranolol first invented and what was its medical use?
History and development Scottish scientist and St. Andrews graduate James W. Black successfully developed propranolol in the late 1950s. He was awarded the Nobel Prize in Medicine for this discovery in 1988. Clinical use: Indications Propranolol is indicated for the management of various conditions including:[1] * Hypertension * Angina pectoris * Tachyarrhythmias * Myocardial infarction * Control of tachycardia/tremor associated with anxiety, hyperthyroidism or lithium therapy. * Essential tremor * Migraine prophylaxis * Cluster Headaches prophylaxis * Tension headache (Off the label use) * Tetralogy of Fallot * Phaeochromocytoma (along with α blocker) * There has been some experimentation in psychiatric areas: o Treating the excessive drinking of fluids in psychogenic polydipsia, o Antipsychotic-induced akathisia, o Aggressive behavior of patients with brain injuries o Post-traumatic stress disorder * Glaucoma While once first-line treatment for hypertension, the role for beta-blocker
