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When I wish to culture cells on microcarrier beads, do the cells need to be on the beads before I load them into the reactor?

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When I wish to culture cells on microcarrier beads, do the cells need to be on the beads before I load them into the reactor?

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The beads and the cells can be loaded into the reactor at the same time, independent of each other. The conditions inside the reactor are such that the cells automatically attach to the beads after they are both loaded into the reactor.

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