When DNA gets replicated, At that time What is the function of proteins?
DNA helicases unwound the two parental strands of the double helical DNA. Single stranded DNA binding proteins attach to the unwound strands, thus preventing them from winding back together. DNA polymerase binds easily to the individual strands which are firmly positioned, and catalyzes the elongation of the leading and lagging strands. The synthesis of leading strand runs continuously, with the help of DNA polymerase on it. In case of lagging strand, RNA primer is needed repeatedly for the synthesis of discontinuous strands termed as Okazaki fragments. DNA primase is one of the important polypeptides that function collectively to build the primer. In the final step, each newly synthesized Okazaki fragment is attached to the completed portion of the lagging strand and this reaction is catalyzed by DNA ligase.
