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When did the increased risk of breast cancer become apparent for women taking estrogen plus progestin compared to women taking placebo pills?

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When did the increased risk of breast cancer become apparent for women taking estrogen plus progestin compared to women taking placebo pills?

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There was no difference in the development of breast cancer during the first 4 years between women taking estrogen plus progestin and those taking placebo pills. After that time, the numbers began to increase. After an average of 5.2 years, there was an increased risk of breast cancer in women taking estrogen plus progestin compared to those taking placebo pills.

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A. There was no difference in the development of breast cancer during the first 4 years between women taking estrogen plus progestin and those taking placebo pills. After that time, the numbers began to increase. After an average of 5.2 years, there was an increased risk of breast cancer in women taking estrogen plus progestin compared to those taking placebo pills.

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