When determining the Overall Impact score, should it equal the arithmetic mean of the scores for the scored review criteria?
Not necessarily. The Overall Impact score considers all scored review criteria as well as all applicable additional review criteria. In addition, an application does not need to be strong in all scored review criteria to be judged likely to have a major scientific impact. Therefore, it is possible for one or more review criteria to overshadow the other review criteria, thus driving the Overall Impact score up or down. Please remember that there is no formula to derive the overall impact/priority score from the individual criterion scores. Reviewers are instructed to weigh the different criteria as appropriate for each application in deriving the Overall Impact score.