WHATS WRONG WITH A BUILDUP OF DOPAMINE?
The buildup of dopamine is bad because it causes an extra sense of pleasure for a short time. This leads to two problems. First, your brain is wired to want to repeat pleasurable activities. Second, research shows long-term use may reduce the amount of dopamine or the number of dopamine receptors in the brain. If that happens, the user may lose the ability to experience pleasure without cocaine–and may also need more and more of the drug just to keep from feeling bad.