Whats the evidence for hormone injections and insemination for unexplained infertility?
There’s a lot of evidence that having hormone injections and insemination (injecting sperm into the womb) can help couples who have unexplained infertility. We found three large summaries of the research (called systematic reviews) that looked at the results of more than 15 studies.[1] [2] [3] Some couples tried insemination after hormone injections. Others had hormone injections only and then had sex around the time of ovulation. • Women who had hormone injections and then had sperm put into their womb were more likely to get pregnant than women who had hormone injections only. We found a third large review with mixed results.[5] • Injecting sperm directly into the womb or the neck of the womb didn’t work any better than having intercourse around the time the woman was ovulating. • But some of the women in the studies didn’t have hormone injections. The women who did had better results, whether they had sex or insemination.