Whats the evidence for clomifene for unexplained infertility?
We found one big summary of the research (called a systematic review). It included five studies called randomised controlled trials. The women in the studies had unexplained infertility. If you have unexplained infertility, it means doctors don’t know why you haven’t been able to get pregnant. • Women who took clomifene were nomore likely to get pregnant than women who didn’t take clomifene.[1] • However, the studies were of mixed quality and some of the women were having other treatments or had tried other treatments in the past. And some hadn’t being trying to get pregnant for very long. So it’s difficult to be sure whether clomifene has a real effect or not..References Hughes E, Brown, J, Collins J, et al. Clomiphene citrate for unexplained subfertility in women (Cochrane review). In: The Cochrane Library. Wiley, Chichester, UK. Glossary systematic reviews A systematic review is a thorough look through published research on a particular topic. Only studies that have been carried out
