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Whats the difference between glucosamine and chondroitin sulfate?

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Whats the difference between glucosamine and chondroitin sulfate?

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GL and CS support each other’s activity, but it’s a case of “opposites attract”. Glucosamine is a simple molecule, CS is large and complex. Although 85 to 90% of oral glucosamine is absorbed in all species tested, almost all of it goes immediately to the liver, where as much as 80% may be broken down. Only the glucosamine that survives this “first pass” can go on to nourish connective tissues. CS is harder to absorb, and absorbs at different rates by species. Biologists are still exploring the absorption of CS and the many ways it can nourish natural lubricant systems.

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