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Whats the best way to treat twin-twin transfusion syndrome (TTTS), one of the most common conditions requiring fetal surgery and the leading cause of mortality in twins?

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Whats the best way to treat twin-twin transfusion syndrome (TTTS), one of the most common conditions requiring fetal surgery and the leading cause of mortality in twins?

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The benchmark, NIH-funded study on TTTS, conducted at 17 centers in the United States, was presented at the annual meeting of the Society for Maternal-Fetal Medicine in San Francisco, and it won’t likely resolve the question of which is the best procedure. The study, led by Timothy Crombleholme, M.D., director of the Fetal Care Center of Cincinnati, shows that the question isn’t which surgical procedure is better, it’s when the procedure is done. Dr. Crombleholme issued a clarion call to fetal care specialists around the world. “The earlier in gestation TTTS is diagnosed, the more severe the syndrome tends to be,” says Dr. Crombleholme, who is also a pediatric surgeon at Cincinnati Children’s Hospital Medical Center. “We have to shift attention to diagnosing this earlier in the progression of the syndrome and being more aggressive about intervention.

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