What’s Passing-Bablock regression?
Another alternate regression procedure is called Passing-Bablock regression, after the authors who described the technique. The slopes are calculated for every combination of two points in the data set, then the slopes are ordered and ranked, and the median value is selected as the best estimate. There is no need for additional information about the relative SDs of the test and comparative methods, thus Passing-Bablock might be more generally applicable than Deming regression. However, Stockl, Dewitte, and Thienpont seem to recommend Deming regression over Passing-Bablock regression in a study of comparative regression statistics. The special calculations needed for Passing-Bablock are not usually found in general purpose statistical packages, so a specialized program is needed. • Passing H, Bablock W. A new biometrical procedure for testing the equality of measurements from two different analytical methods. Clin Chem Clin Biochem 1983;21:709-720. • Stockl D, Dewitte K, Thienpont M. Va
