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Whats more effective: PIO, Progesterone suppositories, Progesterone Gel, or Oral Progesterone?

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Whats more effective: PIO, Progesterone suppositories, Progesterone Gel, or Oral Progesterone?

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All of these may be used in a donor egg IVF cycle. Oral progesterone is metabolized by the gastrointestinal system and its relative uterine levels may be much lower than other products. As a result, oral progesterone is not commonly used as a primary route of progesterone support during treatment. Since the recipient woman has not ovulated during her treatment cycle, her ovary does not make any progesterone to support an early pregnancy. The progesterone medications are critically important in promoting development during the first 9 weeks, when the placenta can take over the role.

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