Whats different about the conditions discussed in Choices & boundaries?
The conditions that were considered in the Choices & Boundaries discussion are different to those previously licensed by the HFEA because they have a combination of features. The conditions in question have all of the following features: • they are later onset and • they are lower penetrance and • they are, in some cases, treatable. The HFEA has licensed conditions that have one or other of these features. For example Huntington’s is later onset and Retinoblastoma is not fully penetrant (although it does have a higher penetrance than inherited breast cancer).It is the fact that inherited breast and bowel cancer have a combination of all of these features that makes them different to others previously licensed by the HFEA.
