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Whats an example of a recent significant outbreak of a disease?

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Whats an example of a recent significant outbreak of a disease?

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One example of a significant outbreak of disease was the outbreak of E-coli that was associated with spinach. It at first began to appear in one or more states and spread to several other states in the United States. It caused fairly widespread illness of about 200 people, several deaths and it was eventually tracked to the Salinas Valley in California, to a lettuce grower in Salinas Valley. But the ultimate cause of the outbreak and source of the E-coli was never established definitively.

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