What e signs and symptoms of diabetes mellitus?
Type 2 diabetes almost always has a slow onset (often years), but in Type 1, particularly in children, onset may be quite fast (weeks or months). Early symptoms of Type 1 diabetes are often polyuria (frequent urination) and polydipsia (increased thirst, and consequent increased fluid intake). There may also be weight loss (despite normal or increased eating), increased appetite, and unreduceable fatigue. These symptoms may also manifest in Type 2 diabetes, though this seldom happens for some years, and sometimes not at all. Clincally, it is most common in Type 2 patients who appear at the doctor with frank poorly controlled diabetes. Thirst develops because of osmotic effects sufficiently high glucose (above the ‘renal threshold’) in the blood is excreted by the kidneys but this requires water to carry it and causes increased fluid loss, which must be replaced. The lost blood volume will be replaced from water held inside body cells, causing dehydration.
Type 2 diabetes almost always has a slow onset (often years), but in Type 1, particularly in children, onset may be quite fast (weeks or months). Early symptoms of Type 1 diabetes are often polyuria (frequent urination) and polydipsia (increased thirst, and consequent increased fluid intake). There may also be weight loss (despite normal or increased eating), increased appetite, and unreduceable fatigue. These symptoms may also manifest in Type 2 diabetes, though this seldom happens for some years, and sometimes not at all. Clincally, it is most common in Type 2 patients who appear at the doctor with frank poorly controlled diabetes. Thirst develops because of osmotic effects – sufficiently high glucose (above the ‘renal threshold’) in the blood is excreted by the kidneys but this requires water to carry it and causes increased fluid loss, which must be replaced. The lost blood volume will be replaced from water held inside body cells, causing dehydration.
