What would be better supercharge or turbocharge my 2006 Lexus IS300?
Without a doubt turbocharge it. The supercharger will barely give you 350whp with lots of supporting mods. Get a T67 turbo from someone like Turbonetics or boost logic and you will never regret it. Keep in mind that the stock automatic can only handle about 300-320whp and anything more is playing with fire. So my advice, get turbo, BUT first invest in a good tranny… either an R154 from a soarer or MKIII Supra, a V160 getrag from the supraTT, or a built auto from someone like boost logic or sound performance. OR if you’re really crazy and money loaded, you can get the sound performance 4spd TH400 transmission which is by far the best automatic you can buy that can handle with ease 1000+whp.