What were the results of the study published today in the New England Journal of Medicine?
Dr. Kreitman: We had a total of 16 patients with hairy cell leukemia. Thirteen of these patients received adequate treatment during the study, for a variety of reasons. Of these 13 patients, all had major responses two with partial responses and 11 with complete remissions. We are still treating the two patients with partial responses, obviously with the goal to get them into complete remission. I should add that all 16 patients had been previously treated with cladribine, a standard chemotherapeutic agent for hairy cell leukemia. Some also had received another standard treatment called pentostatin. All were resistant to chemotherapy, meaning they would not have been expected to have good responses with those agents again, nor with any other agents used to treat hairy cell leukemia. How did you define complete remission in the study? Dr. Kreitman: When you cannot see malignant cells by microscopy of their bone marrow biopsy, and their spleens have to shrink in size to the point that th
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