What were the findings about fractures in the CaD Trial?
Over an average of 7 years, 374 CaD Trial participants had hip fractures. Although women taking the active CaD supplements had 12% fewer hip fractures than those taking placebo tablets, this difference was smaller than expected and could have happened by chance. Another way of looking at this finding is that for every 10,000 women taking active CaD supplements each year, 14 on average had a hip fracture compared to 16 hip fractures for every 10,000 women taking placebo tablets each year. Women taking active CaD supplements had 4% fewer fractures overall when scientists analyzed data on all types of fractures combined, but this could also have happened by chance. When scientists analyzed only the data obtained while participants adhered to the study tablet regimen (when they were taking most of their study tablets), women taking most of their active supplements had 29% fewer hip fractures than those taking placebo (10 compared to 14 cases per 10,000 per year, on average).
