What was the St. Johns wort extract used in this trial?
The St. John’s wort extract used in this study was LI-160, manufactured by Lichtwer Pharma, AG (Berlin, Germany). It was selected because it is a well-characterized and well-studied extract of St. John’s wort that had published literature supporting its possible efficacy in treating depression. The entire supply of St. John’s wort extract used in the study came from one batch and was standardized to between 0.12 and 0.28 percent hypericin. Hypericin is thought to be one of the primary active ingredients in St. John’s wort. 4. What is major depression? Major depressive disorder, also known as major depression, is the most common type of depressive illness. Symptoms usually develop over days, weeks, or months. They can cause distress and/or interfere with the ability to work, study, sleep, eat, and enjoy once-pleasurable activities. The description of a person experiencing a major depressive episode, as found in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (D