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What was the first psychoactive drug produced?

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What was the first psychoactive drug produced?

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Usually when people say “psychoactive drug” they’re not talking about beer. Sure it can be classified as a mind-altering substance, but most likely there have been tons of plants that have been found to produce mind-altering affects on the human brain ever since the beginning of humanity. This question is more opinionated than fact-based.

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