What virus reference stocks are present in the laboratory that have been grown on polio permissive cell lines?
Some rhinovirus and non-polio enterovirus reference strains have been reported to harbour polioviruses. Some of these strains may have been prepared in animals or cell lines of primate origin in which poliovirus can also replicate. Laboratories should confirm the serotype and identity of virus stocks and reference strains (e.g. by neutralization tests or plaque reduction assay), and exclude the presence of polioviruses.
