What undeclared ingredients were found?
An FDA analysis found that the undeclared active pharmaceutical ingredients in some of these products include • sibutramine, a controlled substance that can cause high blood pressure, seizures, abnormally rapid heart rate (tachycardia), palpitations, heart attack or stroke. It can also interact with other medications and increase patients’ risk of unexpected bad side effects (adverse reactions). Sibutramine’s safety has also not been established in pregnant and lactating women, or in children younger than 16. • rimonabant, a drug not approved for marketing in the United States, has been associated with increased risk of depression and suicidal thoughts. In Europe, where it is approved, rimonabant has been linked to five deaths and 720 adverse reactions over the last two years.
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