What types of proteins can be made inducible?
A wide variety of different types of protein-hbd fusions have been reported, including a number of types of DNA binding protein and RNA binding proteins, kinases, and enzymes (Table 1). The primary consideration is that the protein in question have a known function, so it can be determined that the addition of the ligand binding domain does not alter protein function. Additionally, a general knowledge of the domain structure of the protein is useful, so that insertion of the ligand binding domain does not disrupt any important functional domain.
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