What types of misadministration could occur?
Misadministration means giving the radiopharmaceutical to the wrong patient, giving the wrong radiopharmaceutical or wrong activity to the patient, or unjustified examination of pregnant or lactating female patients. Another type of misadministration is to use the wrong route of administration, which includes complete extravascular injections that can result in very high absorbed exposure at the injection site especially if the volume is small, the activity is high, and the radiopharmaceutical has a long retention time. The definition of wrong activity should be made locally. In general, a variation of ±25% from the prescribed activity is regarded as acceptable in diagnostic applications.