What types of genomic experiments can be run on paraffin embedded specimens?
Since DNA fragments of up to 400 bp and RNA fragments of up to 150 nucleotide in length can be routinely isolated from the specimens, mutation detection, SNP analysis, detection of translocation, microRNA quantitation are examples of experiments that have been successfully run from these specimens. Recent studies have shown that formalin fixed paraffin embedded tissues can be used gene expression profiling.