What tumors are most often associated with hypercalcemia?
The tumors most often associated with hypercalcemia in dogs are lymphoma and anal sac adenocarcinoma. Often the lymphoma is in the cranial mediastinal region, or it can be in the gastrointestinal tract or bone marrow. Other tumors causing hypercalcemia include thymoma, carcinomas (bronchogenic, pancreatic, skin, etc.) and multiple myeloma. In cats, lymphoma and squamous cell carcinomas are the most common causes of hypercalcemia. Other tumors causing hypercalcemia in cats include osteosarcoma, fibrosarcoma, bronchogenic carcinoma and multiple myeloma.