What time of day is best to use MI Paste?
In terms of the binding properties of MI Paste, CPP-ACP binds to oral soft tissues, to dental pellicle and also to plaque. This binding elevates the salivary levels of calcium and phosphate for extended periods. For this reason, MI Paste works best in patients when it is applied at night before bed, since the salivary clearance rate is low during sleep. In patients who need intensive treatment, then a twice daily application is sufficient in most individuals. It is recommended that MI Paste be applied immediately after flossing and brushing with a 1000 ppm fluoride toothpaste, particularly at night before bed. RECALDENT CPP-ACP, the active ingredient of MI Paste, is extremely effective for desensitizing, and this is due to the combination of surface effects and its ability to remineralize hard tissues. Some patients who have generalized cervical dentinal hypersensitivity, may also have dental erosion, and thus one needs to look carefully at their lifestyle (using particularly the resti