What tests were used to determine eligibility for SELECT?
Tests included a digital rectal examination (DRE) and a prostate-specific antigen (PSA) test. During a DRE, a doctor inserts a gloved finger into the rectum and feels the prostate gland through the rectal wall to check for bumps or abnormal areas. The PSA test measures the level of PSA (a protein produced by the cells of the prostate gland) in the blood. PSA levels can rise due to cancer or benign (not cancerous) conditions. Doctors often use the PSA test and DRE as prostate cancer screening tests in men who have no symptoms of the disease. To be eligible for the SELECT trial, participants had to have a DRE that found no signs of prostate cancer and a total PSA level less than or equal to 4.0 ng/ml. During the trial, DREs and PSA tests are suggested, but not required, on an annual basis throughout the course of the study. 9. Who pays for these tests? Physician, medical examination, and general clinic costs, including DREs, are charged to the participant in the same way as if he were no
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