What tests should be done for the urine phosphate and creatinine assessment?
The urine phosphate and creatinine is needed for measurement of tubular phosphate reabsorption (Tmp/GFR), see appendix A.3. It requires a urine sample to be sent to biochemistry lab for urine phosphate and urine creatinine. Centers should talk to their biochemistry lab before sending the sample. Measurement of tubular phosphate reabsorption (Tmp/GFR) is optional. It is recommended at the end of chemotherapy; see protocol v1.3, section 8.3.4, page 24 and appendix A. [ Back To Questions ] Q.52 Interferon alfa-2b and Male Fertility There have been very rare cases of a drop in sperm count in men who have been treated with interferon alfa-2b. This is probably due to the anti-proliferative effects of interferon alfa-2b and appears to be a non-permanent effect. To date there is no evidence that interferon alfa-2b will have any genetic effect on the sperm. The difficulty generally would be in knowing if the patient had a fertility problem prior to commencement of interferon therapy, however, i
