What test principle does the Accu-Chek Performa system use, and why?
The Accu-Chek Performa system uses an electrochemical test principle instead of the photometric principle used in the Accu-Chek Active system, Accu-Chek Compact system, and Accu-Chek Go system. Electrochemical biosensors such as those in the Accu-Chek Performa system provide high levels of sensitivity and specificity. In an electrochemical test principle, glucose dehydrogenase enzymatically reacts with glucose in a sample causing the release of an electron that then reacts with a mediator. The modified mediator is subsequently electrochemically converted to its initial state upon application of a voltage difference between the electrodes, resulting in a small electric current that is detected by the system.
