What subsequent research and developments have occurred since the publication of the New England Journal of Medicine study?
Interestingly, a subsequent “half-point” analysis of a large long-term study of diabetics taking Avandia suggested that there was no increase in the risk of heart attacks but rather, an increase in the occurrence of heart failure. From the regulatory side of things, the U.S. Food and Drug Administration narrowly voted 8 to 7 against removing Avandia from the market. Of note, a Nov. 1 notice from Health Canada stipulates that Avandia is no longer approved as the sole medication – it is often used in combination with other drugs – for Type 2 diabetes. The exception to this would be cases where another widely used diabetes drug, Metformin, is contraindicated or not tolerated. The notice also includes other restrictions on the use of Avandia. Reluctance to use Avandia is particularly warranted for patients already at high risk of a heart attack as a result of other risk factors. So what are patients and their physicians supposed to do? The available data show that controlling diabetes with
Related Questions
- What subsequent research and developments have occurred since the publication of the New England Journal of Medicine study?
- How does this differ from Dr. Cowans study published in the new England Journal of Medicine?
- What were the results of the study published today in the New England Journal of Medicine?
