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What should I do when my QC zone sizes are out of range for one or two antimicrobics when testing my Mueller Hinton Agar?

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What should I do when my QC zone sizes are out of range for one or two antimicrobics when testing my Mueller Hinton Agar?

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A. First, try a different lot number or a different manufacturer of the antibiotic disk. Make sure you are keeping your penicillin, ampicillin, and cephlosporins in the freezer, since they are particularly labile. Also, make sure your dispenser is kept in an airtight container with fresh desiccant and indicator (DesiView™, Cat. no. DV10) in order to keep out moisture.

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