What should I discuss with my healthcare provider before taking sibutramine (Meridia)?
Do not take sibutramine without first talking to your doctor if you • have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days; • are or have been depressed; • have bleeding problems; • have anorexia nervosa; • are taking an appetite suppressant; • have high blood pressure; • have heart disease, irregular heartbeats, congestive heart failure, or a history of stroke; • have epilepsy or another seizure disorder; • have gallstones; • have glaucoma; • have liver disease; or • have kidney disease. You may not be able to take sibutramine, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above. Sibutramine may interact with other medicines and cause a condition called Serotonin Syndrome. This syndrome requires immediate medical attention and may include one or more of the following symptoms: anxiety, restlessness, loss of consciousness, confusion,
