What should I discuss with my doctor before taking hydrochlorothiazide and spironolactone?
• kidney disease or are unable to urinate; • high potassium levels (hyperkalemia); or • if you are taking potassium supplements. If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication: • diabetes; • heart disease; • cirrhosis or other liver disease; • a breathing disorder; • gout; • lupus; • an allergy to sulfa drugs; • a pancreas disorder; or • if you are using another blood pressure medication or a steroid.