What should be done if acetaminophen toxicity is suspected?
A physician should evaluate the individual immediately. Remember that bringing the bottles of acetaminophen and all of the person’s other medications to the emergency room is always useful. The risk that an acetaminophen overdose will cause liver injury correlates with the blood level of acetaminophen relative to the time the drug was taken. Physicians, therefore, are able to estimate the patient’s probability of developing liver injury after an overdose. To make this determination, they obtain the patient’s history of acetaminophen ingestion and measure the blood level of the drug. With this information, the doctor then can refer to a table (nomogram) that provides an estimate of the risk of developing liver injury. The accuracy of this estimate, however, depends on the reliability of the time of ingestion and whether the acetaminophen was taken over a period of time or all at once. With suspected acetaminophen overdose, the doctors usually will pump (gavage) the patient’s stomach to
