What PSA Velocity* should be used to recommend a prostate biopsy?
This issue is in flux at present. Currently, it is thought that a PSAV between 0.3 and 0.5 should be used to recommend a biopsy In men with a PSA lower than 4. New 2007 guidelines will be issued by the National Comprehensive Cancer Center Network and the American urological Association this year, and I believe they will recommend 0.4 and 0.35, respectively. It looks as if prostate cancer should be diagnosed before the PSA is above 4 and the PSA velocity gets above 0.5. Otherwise, a lot of men will be detected with cancer that already has spread to the margins of the prostate gland or beyond. *PSA Velocity is the rate at which PSA rises in a year.
