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What protecting groups are used in polyamino acids?

April 26, 2017acids groups polyamino Protecting Used

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What protecting groups are used in polyamino acids?

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In general, the carbobenzyloxy (Z) group is used to protect the side chain amino groups, and the Benzyl (Bzl) group is used to protect the side chain carboxyl groups. For amino acids which contain a hydroxyl side chain, the hydroxyl groups are protected by using the Z group for tyrosine (Tyr), either the Z or Acetyl (Ac) groups for Serine (Ser), and the Trichloroethyl group for Threonine (Thr).