What programs are used for chromosome mapping?
• crimap: This program has been used for chromosome mapping for years. It has options which can generate maps, calculate order probablities, and printout recombination data. It works on .gen files with data from CEPH-style families. It is written in K&R type C code, and Phil Green (the author) has successfully run it on UNIX, DOS, VMS, and Macintosh systems. It is not available via anonymous ftp. • multimap:This Lisp-based expert system uses an customized version of crimap to create a chromosome map. It is available via anonymous ftp from genome1.hgen.pitt.edu. The authors (T Matise, M Perlin, and A Chakravarti) continute to improve the code, add new functions, and provide excellent support. When used with the crimap chrompic option (to find double-recombinations to identify possible errors), it is incredibly useful. This is Unix-only (supported for Dec-Ultrix, HP9000, and Suns). The customized crimap version (called lispcri) is distributed at the ftp site, but was not meant to be used