What physiological factors affect the secretion of growth hormone from the pituitary?
Growth hormone is secreted in a pulsatile fashion from the anterior pituitary gland by a feedback mechanism from the hypothalamus. Both an inhibitory peptide, Growth hormone release – inhibiting hormone, and a stimulatory peptide, growth hormone – releasing hormone, play an important role in its secretion. Physiological factors affecting the secretion of growth hormone include: age, exercise, nutritional status, sleep, level of stress and development growth. More specifically, growth hormone secretion is stimulated by exercise, sleep and fasting, while growth hormone is decreased by food intake, obesity and aging.
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