What percentage of CRC cancer patients have low CEA values (below the CEA manufacturer’s cut-off for utility during monitoring)?
For many CRC patients with biopsy confirmed cancer, CEA levels are not measurable above the physiological background. Data was taken from three independent studies19-21 and presented directly in Table 2 on the next page to assess the need for an additional CRC monitoring tool. Approximately 50% of all CRC patients with low CEA values can not use the CEA test to monitor their cancer because their CEA levels fall below the manufacturer’s defined physiological background level. In the table below, CEA Low Responders is the term given for biopsy positive cancer patients with low CEA values. All of the numbers in the table have been published in the referenced papers. Table 2.