What other indications may be considered for administration of Pamidronate Disodium?
Pamidronate Disodium may be considered for very select individuals who have low bone density or osteopenia. Osteopenia is defined as hip bone mineral density measurement (BMD) that is between 1 – 2.5 standard deviations below the young adult female mean (T-score less than -1 and greater than –2.5). In order for osteopenia to be considered for coverage, the following selection criteria must be met and documented: • The diagnosis must be made by a central DEXA scan measurement with a T-score less than -1 and greater than -2.5; • The patient has intolerance to two or more antiresorptive agents or has had a 12 month trial of oral biphosphonates without documented improvement; and • The patient must have the associated risk factors for fracture.
