What non-genetic factors may cause nephrogenic diabetes insipidus in Bartters syndrome?
Physiology principle 10: The most common cause of non-genetic AQP2 deficiency type of nephrogenic diabetes insipidus is lithium, but this is not applicable here, as neither the patient nor his mother took lithium. Temporary nephrogenic diabetes insipidus can be observed with obstructive uropathy (especially after release of obstruction), hypokalaemia and hypercalcaemia (Table 4).
