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What methods are used to determine molecular weights reported in the Sigma-Aldrich Certificate of Analysis?

April 26, 2017analysis Certificate determine methods Molecular reported Sigma-Aldrich Used weights

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What methods are used to determine molecular weights reported in the Sigma-Aldrich Certificate of Analysis?

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Two methods are used – (1) Viscosity and (2) either Gel Permeation Chromatography Multi-Angle Laser Light Scattering or Gel Permeation Chromatography Right-Angle Laser Light Scattering (GPC MALLS/GPC RALLS) Molecular weight data by viscosity is provided for all polyamino acids. GPC MALLS/GPC RALLS molecular weight is provided for only selected polyamino acids. Please see the product listing for information and contact Sigma Technical Services for further details.