WHAT METHOD IS USED FOR QUALITY CONTROL OF CUSTOMARRAY CHIPS?
Each and every synthesized CustomArray chip is quality tested by hybridization with Cy5-labeled random 9-mer oligonucleotide targets. This hybridization is used to visualize the synthesis at every electrode as well as irregular spot morphology. All hybridization data are first analyzed automatically using rigorous statistical criteria, and then inspected visually by an independent reviewer for the final ‘pass’ or ‘fail’ decision to ensure the high quality of chips shipped to our customers. The arrays that have passed the inspection are stripped of the hybridized 9-mers, washed, and dried for shipment.
