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What medications should a clinician use with a patient who is highly nicotine dependent?

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What medications should a clinician use with a patient who is highly nicotine dependent?

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The higher dose preparations of nicotine gum, patch, and lozenge have been shown to be effective in highly dependent smokers. Also, there is evidence that combination NRT therapy may be particularly effective in suppressing tobacco withdrawal symptoms. Thus, it may be that NRT combinations are especially helpful to highly dependent smokers or those with a history of severe withdrawal.

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